Our Technology

Pepdura is built upon the pioneering research conducted by The Gruber Lab at the Medical University of Vienna, alongside esteemed colleagues from universities across Austria and Australia. Over the past decade, our collaborative research has delved deep into understanding the structure-activity relationships and pharmacological mechanisms of nature-derived peptides that target G protein-coupled receptors (GPCRs).

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GPCRs are crucial for virtually all physiological processes, with most bodily regulatory functions mediated by small, ephemeral peptides. The pharmaceutical industry has long sought to replicate the effects of these regulatory peptides - encompassing hormones, cytokines, neuropeptides, and more - using synthetic chemicals or antibodies. Our team's groundbreaking work has led to significant enhancements in the pharmacological attributes of these peptides.

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A key breakthrough has been the development of innovative chemical cyclization techniques. These advancements not only enhance the biological stability of these molecules but also enable the oral delivery of peptide-based medications. This opens new pathways for delivering safer, more effective treatments directly to patients, revolutionizing how we approach pharmaceutical development.